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Vascular and metabolic disorders

CHIRI is identifying new treatments for age-associated blood vessel disorders including bleeding and clotting disorders, heart disease and stroke. The institute is also targeting blood vessel growth and function to treat age-associated cancers, blood-vessel inflammatory disorders with ageing, age-linked energy disorders, liver disorders and age-associated infectious diseases.

Inflammation, infectious disease and wounds

CHIRI’s research aims to stop the decline in immune function with ageing, target the immune system to treat adult cancers and target immune function for treatment of infection and muscle repair.

Neurodegenerative disorders

CHIRI explores novel and new approaches to the prevention and treatment of Alzheimer’s disease and other dementias, as well as the prevention and treatment for neurodegenerative diseases such as multiple sclerosis and epilepsy.


CHIRI is researching novel interventions for age-associated cancers such as breast, pancreas and prostate cancer and melanoma. The institute’s focus is on how the immune system influences cancer risk and progression and trialling novel interventions.